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Vitamin B12 Deficiency

This Medical Laboratory Science lesson in Hematology supports laboratory science learning and laboratory interpretation for medical laboratory students and professionals.

Vitamin B₁₂ deficiency laboratory patterns, macrocytic anemia, neurologic context, Schilling concepts, and assay limitations.

Intermediate32 min read18 sectionsHematology
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Learning Objectives

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Learning Objectives

Learning Objectives

Section: Learning Objectives

Laboratory medicine focus, patterns suggest differentials; confirmatory tests and clinical correlation establish diagnosis.

  • Recognize B₁₂ deficiency hematologic patterns on CBC and smear
  • Interpret serum B₁₂ with institutional reference intervals and assay caveats
  • Identify when adjunct MMA/homocysteine testing supports diagnosis
  • Correlate pernicious anemia and malabsorption contexts

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