Overview
Systematic WBC interpretation before result release.
Classification
| Step | Action |
|---|---|
| Preanalytical | Reject/recollect per policy |
| Quantitative | WBC + absolute counts |
| Flags | Reflex smear criteria |
| Morphology | 100-cell differential when indicated |
| Synthesis | Reportable pattern with hedged language |
| Notification | Critical values per CLSI GP47 local policy |
Morphologic Features
Cross-lineage smear review sequence.
Laboratory Characteristics
- Document LIS verification steps
Reference Intervals
Use report-specific intervals only.
Clinical and Laboratory Significance
Workflow ensures integrated interpretation across Module 6.
Differential Considerations
Pattern branch follows workflow completion.
Comparison Tables
Classification Frameworks
Laboratory Notes
- Module assessment validates integrated competency.
References
Authoritative textbooks, guidelines, and reviews supporting this reference entry. Verify reference intervals, critical limits, and reflex criteria against institutional protocols and current guideline editions.
Textbooks
- McPherson RA, Pincus MR. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Elsevier; 2021.
- Rodak BF, Carr JH. Rodak's Hematology: Clinical Principles and Applications. 6th ed. Elsevier; 2020.
- McKenzie SB, Williams JL. Clinical Laboratory Hematology. 4th ed. Pearson; 2022.
Professional Monographs
- Barnes PW, McFadden SL, Machin SJ, Doig K. Laboratory Hematology Practice. Wiley-Blackwell; 2012.
CLSI and Professional Guidelines
- Clinical and Laboratory Standards Institute. Reference Leukocyte (WBC) Differential Count (Proportional) and Evaluation of Instrumental Methods; Approved Standard. CLSI document H20-A2. CLSI; 2007.
- Clinical and Laboratory Standards Institute. Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory; Approved Standard. CLSI document EP28-A3c. CLSI; 2010.
- Clinical and Laboratory Standards Institute. Management of Critical- and Significant-Risk Results. CLSI guideline GP47-Ed1. CLSI; 2015.
WHO Publications
- World Health Organization Classification of Haematolymphoid Tumours. 5th ed. Lyon: International Agency for Research on Cancer; 2022.
Frequently Asked Questions
Common questions about using this WBC Interpretation Workflow . Checklist additional test references Medical Laboratory Library reference in Medical Laboratory Science education.
What is the WBC Interpretation Workflow . Checklist laboratory reference?
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