Overview
Leukocytes classified by myeloid and lymphoid lineage.
Classification
| Class | Members |
|---|---|
| Granulocytes | Neutrophils, eosinophils, basophils |
| Mononuclear | Monocytes, lymphocytes |
Morphologic Features
See cell-line Library entries for morphology detail.
Laboratory Characteristics
- Automated differential percentages
- Absolute counts derived from WBC
Reference Intervals
Verify institutional intervals, no universal ranges.
Clinical and Laboratory Significance
Overview only, interpret via cell-line and integrative lessons.
Differential Considerations
Comparison Tables
Classification Frameworks
Laboratory Notes
- Cross-link Module 3 white-cell-differential for instrument mechanics.
References
Authoritative textbooks, guidelines, and reviews supporting this reference entry. Verify reference intervals, critical limits, and reflex criteria against institutional protocols and current guideline editions.
Textbooks
- McPherson RA, Pincus MR. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Elsevier; 2021.
- Rodak BF, Carr JH. Rodak's Hematology: Clinical Principles and Applications. 6th ed. Elsevier; 2020.
- McKenzie SB, Williams JL. Clinical Laboratory Hematology. 4th ed. Pearson; 2022.
Professional Monographs
- Barnes PW, McFadden SL, Machin SJ, Doig K. Laboratory Hematology Practice. Wiley-Blackwell; 2012.
CLSI and Professional Guidelines
- Clinical and Laboratory Standards Institute. Reference Leukocyte (WBC) Differential Count (Proportional) and Evaluation of Instrumental Methods; Approved Standard. CLSI document H20-A2. CLSI; 2007.
- Clinical and Laboratory Standards Institute. Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory; Approved Standard. CLSI document EP28-A3c. CLSI; 2010.
- Clinical and Laboratory Standards Institute. Management of Critical- and Significant-Risk Results. CLSI guideline GP47-Ed1. CLSI; 2015.
WHO Publications
- World Health Organization Classification of Haematolymphoid Tumours. 5th ed. Lyon: International Agency for Research on Cancer; 2022.
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