Overview
Module 13 library supplement, links to detailed lookup entries without duplicating Academy lessons.
Classification
| Assay | Pathway | Key association examples (not exclusive) |
|---|---|---|
| PT/INR | Extrinsic/common | Warfarin, liver disease, FVII deficiency |
| aPTT | Intrinsic/common | Heparin, hemophilia, LA, FXI deficiency |
| Fibrinogen | Common | DIC consumption, liver failure |
| D-dimer | Fibrinolysis marker | VTE, DIC, inflammation, nonspecific |
| Thrombin time | Terminal fibrin | Hypo/dysfibrinogenemia, heparin, FDPs |
| Mixing study | Deficiency vs inhibitor | Reflex before factor panel when indicated |
Morphologic Features
Integrate platelet count and smear with all coagulation interpretation.
Laboratory Characteristics
- Reagent ISI and sensitivity, institutional reference intervals only
Reference Intervals
No universal numeric values, use patient report intervals.
Clinical and Laboratory Significance
Capstone: coagulation-interpretation-workflow Academy lesson.
Differential Considerations
See vwd-hemostasis-disorders-lookup for disease comparison.
Comparison Tables
See mixing-study-interpretation-lookup and coagulation-test-panels-lookup.
Classification Frameworks
Laboratory Notes
- Library-only supplement entry; confirm local method notes before clinical application.
References
Authoritative textbooks, guidelines, and reviews supporting this reference entry. Verify reference intervals, critical limits, and reflex criteria against institutional protocols and current guideline editions.
Textbooks
- McPherson RA, Pincus MR. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Elsevier; 2021.
- Rodak BF, Carr JH. Rodak's Hematology: Clinical Principles and Applications. 6th ed. Elsevier; 2020.
- McKenzie SB, Williams JL. Clinical Laboratory Hematology. 4th ed. Pearson; 2022.
CLSI and Professional Guidelines
- Clinical and Laboratory Standards Institute. Collection, Transport, and Processing of Blood Specimens for Testing Plasma-Based Coagulation Assays and Molecular Hemostasis Assays. CLSI document H21-A5. CLSI; 2008.
- Clinical and Laboratory Standards Institute. Collection, Transport, and Processing of Blood Specimens for Testing Plasma-Based Coagulation Assays. CLSI document H21. CLSI.
- Clinical and Laboratory Standards Institute. Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory; Approved Standard. CLSI document EP28-A3c. CLSI; 2010.
- Clinical and Laboratory Standards Institute. Management of Critical- and Significant-Risk Results. CLSI guideline GP47-Ed1. CLSI; 2015.
- International Society on Thrombosis and Haemostasis. Guidelines for the diagnosis of von Willebrand disease. ISTH; 2021.
WHO Publications
- World Health Organization. Haemophilia: diagnosis and management. WHO; 2020.
Frequently Asked Questions
Common questions about using this Coagulation Laboratory . Module Lookup foundational topics Medical Laboratory Library reference in Medical Laboratory Science education.
What is the Coagulation Laboratory . Module Lookup laboratory reference?
Coagulation Laboratory . Module Lookup is a Foundational Topics entry in the LabPedia Medical Laboratory Library, written for Medical Laboratory Science reference lookup.
How should students use this medical laboratory encyclopedia page?
Read the structured sections for quick orientation, then follow related links into Academy lessons or Challenge Center practice when you need teaching or assessment.
Does this page replace laboratory textbooks?
No. It is a concise educational laboratory reference. Use recognized laboratory medicine sources and your institutional procedures for definitive practice decisions.
Where can I find related laboratory tests?
Use related links on this page when present, or browse Laboratory Library discipline catalogues for laboratory tests and interpretation references.
Is this content part of Medical Laboratory Education on LabPedia?
Yes. Library references support Medical Laboratory Education alongside Academy courses, medical laboratory quizzes, and laboratory case studies.
Can reference details vary between laboratories?
Yes. Methods, intervals, and reporting conventions vary. Always confirm details against your laboratory’s current protocols.
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