Search

Acute Hemolytic Transfusion Reactions

This Medical Laboratory Science lesson in Blood Bank supports laboratory science learning and laboratory interpretation for medical laboratory students and professionals.

Execute the laboratory's stop-and-investigate response to a suspected acute hemolytic transfusion reaction, clerical check, visual inspection for hemoglobinemia, DAT, and repeat ABO/Rh typing, and recognize the findings pattern that supports ABO-incompatible hemolysis.

Advanced32 min read15 sectionsBlood Bank
Section 1 of 150%

Learning Objectives

Getting started

Section 1 of 15

Learning Objectives

Learning Objectives

Section: Learning Objectives

Each objective below describes a transfusion-service laboratory competency, investigating and interpreting adverse transfusion reactions, not delivering bedside treatment.

  • Describe the laboratory's immediate stop-and-investigate response when an acute hemolytic transfusion reaction (AHTR) is suspected, including the clerical check, visual inspection of post-transfusion plasma, and specimen/unit retention
  • Interpret the core AHTR workup panel, clerical check, visual hemolysis inspection, DAT, and repeat ABO/Rh typing, and recognize the laboratory findings pattern that supports ABO-incompatible hemolysis
  • Distinguish laboratory findings that support AHTR from those that point toward a non-hemolytic reaction category, and identify when extended workup is indicated

Section 1 of 15